Cell replacement and visual restoration by retinal sheet transplants
نویسندگان
چکیده
منابع مشابه
Structure and function of embryonic rat retinal sheet transplants.
PURPOSE To evaluate retinal sheet transplants in S334ter-line-3 retinal degenerate rats by comparing visual responses recorded electrophysiologically with morphology based on light and electron microscopy. METHODS S334ter-line-3 retinal degenerate rats (n = 7) received retinal sheet transplants between postnatal days 28 and 31. The donor tissue was derived from transgenic embryonic day 19 (E1...
متن کاملAdult rabbit retinal transplants.
PURPOSE To study the survival of adult retinal grafts prepared in a physiologically optimized way. METHODS Twenty-three rabbits received an adult full-thickness rabbit retinal transplant positioned under the host retina, using a vitrectomy technique. The transplants were prepared using a procedure based on a previously described in vitro model used for physiological experiments on the adult r...
متن کاملIntraocular retinal transplants.
Embryonic rat retinae transplanted into the anterior chamber of adult rat eyes of the same or different strain survive and grow. Light and electron microscopic studies show that the transplants undergo histogenetic differentiation, resulting in the development of mature inner and outer layer neurons and Müller glial cells. Vascular connections develop between the host iris and the retinal trans...
متن کاملDevelopment of retinal transplants.
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The expression of locomotor activity by golden hamsters is temporally controlled by circadian oscillators contained within the suprachiasmatic nucleus (SCN). A genetic mutation has been found that alters the freerunning period of the locomotor activity rhythm from the wild-type value of approximately 24 hours to approximately 20 hours in homozygous mutants. It has been shown previously that a t...
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ژورنال
عنوان ژورنال: Progress in Retinal and Eye Research
سال: 2012
ISSN: 1350-9462
DOI: 10.1016/j.preteyeres.2012.06.003